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What is the primary route of transmission for endotoxins?

  1. Inhalation

  2. Direct contact

  3. Ingestion

  4. Vector-borne

The correct answer is: Inhalation

The primary route of transmission for endotoxins is through inhalation. Endotoxins are components of the outer membrane of Gram-negative bacteria and are released when these bacteria die or undergo division. When particles containing endotoxins are aerosolized in the environment, they can easily be inhaled into the lungs. This exposure can lead to a range of health effects, especially respiratory issues. While endotoxins can also be encountered through direct contact with contaminated surfaces or ingestion of contaminated food or water, these routes are secondary compared to inhalation, which is particularly significant in environments such as hospitals or industries that handle bacteria. Additionally, endotoxins are not typically transmitted via vectors like insects, making inhalation the most prominent and concerning route for exposure.